Disney’s Frozen Head
Irreverent Health-055-Disney's Frozen Head


How long do we even want to live?  A famous longevity researcher gets $10m to advance the field.  Will they ever be able to thaw Disney's head?  Do we care?

How long do we even want to live?  A famous longevity researcher gets $10m to advance the field.  Will they ever be able to thaw Disney’s head?  Do we care?


The conversation begins with a discussion about a recent trip to Iceland and the unique language and experiences encountered. The hosts then transition to talk about the end of a business accelerator program and the bittersweet feelings associated with it. They delve into the topic of Sinclair’s recent $10 million investment and the challenges of navigating the regulatory landscape in the face of rapid innovation. The conversation explores the need for revenue generation in order to support transformative ideas and the changing dynamics of personal branding. The hosts also touch on the concept of cryogenics and its place in the realm of biohacking. In this conversation, Matt and Tom discuss cryonics and life extension. They explore the concept of cryogenic preservation and the potential for extending human life through scientific advancements. They also discuss the shift from offense to defense in biohacking and the challenges of cryogenic preservation. The possibility of salvaging DNA from extreme cold is considered, as well as the potential benefits of Sinclair’s research. The conversation delves into the idea of cloning and aging acceleration, and the consequences of making deals with the unknown. They emphasize the importance of maintaining a high bullshit meter and discuss the fear of unknown consequences. The conversation concludes with a discussion of personal projects, including Matt’s book on metacognition and multidisciplinary thinking.


  • The pace of innovation has outstripped the ability of regulatory systems to keep up, creating challenges for companies and individuals seeking to bring new ideas to market.
  • In the current landscape, revenue generation is often necessary to support transformative ideas and ensure their continued development and impact.
  • Personal branding plays a significant role in gaining attention and support for innovative ideas, but it is important to evaluate the intentions and credibility of individuals and companies in the space.
  • Early biohacking and cryogenics were once considered cutting-edge ideas, highlighting the ever-evolving nature of scientific and technological advancements. Cryonics and life extension are topics of interest and speculation.
  • Biohacking has shifted from offense to defense.
  • Cryogenic preservation poses challenges and risks.
  • Salvaging DNA from extreme cold is a possibility.
  • Sinclair’s research has potential benefits for life extension.
  • Cloning and aging acceleration are potential future scenarios.
  • It is important to be skeptical and maintain a high bullshit meter.
  • The fear of unknown consequences is a factor in exploring new technologies and treatments.
  • Personal projects, such as writing a book, require dedication and focus.


00:00 Introduction and Iceland Trip
03:46 Goldman Sachs Business Accelerator
05:06 Discussion on Sinclair’s $10 Million Investment
09:03 The Lethargic System and Pace of Innovation
11:12 The Changing Landscape of Innovation
18:06 The Need for a Revenue Source
24:37 The New Yardstick for Evaluating Intentions
30:43 Early Biohacking and Cryogenics
33:37 Exploring Cryonics and Life Extension
35:12 Switch from Offense to Defense in Biohacking
36:05 The Challenges of Cryogenic Preservation
36:50 The Possibility of Salvaging DNA from Extreme Cold
38:11 Speculating on the Future of Life Extension
39:17 The Potential Benefits of Sinclair’s Research
40:07 Cloning and Aging Acceleration
40:50 The Consequences of Making Deals with the Unknown
41:19 Maintaining a High Bullshit Meter
42:05 The Fear of Unknown Consequences
43:26 Speculating on Future Scenarios
44:13 Wrapping Up Personal Projects
45:01 Matt’s Book on Metacognition and Multidisciplinary Thinking